Is humor in the testosterone?

What happens when two of the smartest, wittiest men in the world get together to discuss world issues?
You get Fareed Zakaria and Jon Stewart Leibovitz in the Daily Show studios in New York.
Besides the witty banter (that invariably happens everytime Zakaria is a guest on the show---three, to be precise), I can't help but smile at the irony of the situation.
A third generation American jew and a first generation American muslim sit down to crack the Islamic terrorism problem. The jew makes a joke about the fatwa and the muslim makes a joke about the kosher and all seems to be well with the world.

But my question is not about jews or muslims or religion, but the other big equal opportunity concern: Why is it always the men? Why cant two women sit and discuss religious fanaticism and be funny? Hell, they can discuss Charlie Brown and not be funny. Is humor in the testosterone?

Why are the people that make you roll on the floor with laughter at midnight always a Bill Maher or a Jon Stewart or a Jay Leno? Why does Conan O'Brien merely have to toss his head and do a jig or mimic Dubya to make your sides split uncontrollably?

With all due respect to women, Ellen Degeneres is just not funny. Tina Fey and Amy Poehler did great as Weekend Update anchors but that’s contrived. You can't put Fey in Bill Maher’s chair for instance and expect her to be insanely funny with a guest that’s as boring as Alec Baldwin or as unpredictable as O’Reilly. In fact the one time Fey was on the Daily Show, she was barely funny. Even someone like Stewart is out of the running trying to instigate the funny side of his women guests (Sandra Bullock excepted). Not that his show needs any help in the humor department ---a four man one woman team is pretty self-sufficient (point to be noted: Samantha B never instigates the kind of raving applause that Steve Colbert or Rob Cordury are invariably greeted with, and for good reason).

And it’s not just restricted to the real world:

Would we find it so hilariously witty and endearingly philosophical if Calvin were Calvina? Hell, even Hobbes is male! So are Bart and Homer, Dennis the Menace and Jughead Jones. Susie Derkins is smart and earnest and Lisa Simpson is brainy and righteous---just never funny.

Chandler and Ross are funny, old Woody is hilarious, Frasier is witty, Jerry Seinfeld is a natural comedian, Charlie Chaplin and Laurel and Hardy are the most hilarious characters that ever walked the earth ---they all have just one thing in common… they are all men….

Is it just my inherent bias or is humor in the testosterone?